Synchronous multicentric glioblastoma with PNET and O subtypes: Possible pathogenesis

Kai Rui Wan, Nicolas K.K. King, Sharon Y.Y. Low, Yih-Yian Sitoh, Hwei Yee Lee, Chin Fong Wong, Wai Hoe Ng

Date of publication: 04-Mar-2014

Background:Glioblastomas (GBM) are highly infiltrative, cellular and mitotically active tumors with large histologic variations within and between tumours. Several subtypes have been described including the GBM with oligodendroglial differentiation (GBM-O) and primitive neuroectodermal tumour components (GBM-PNET). We report the first described case of a patient with synchronous multi-centric GBM-O and GBM-PNET components.

Orbital tuberculosis with coexisting fungal (Aspergillus flavus) infection

Sunkara Srikanth Reddy, Devi Chendira Penmmaiah, Alugolu Rajesh, Madhusudan Patil

Date of publication: 04-Mar-2014

Background:A coexisting invasive fungal and tubercular involvement of the skull base is a rare event. Co-infection has been reported with involvement of paranasal sinuses and middle ear cleft.

Long-term follow-up in two cases of intracranial Rosai–Dorfman Disease complicated by incomplete resection and recurrence

Diones Rivera, Miguelina Pérez-Castillo, Belkis Fernández, Peter Stoeter

Date of publication: 28-Feb-2014

Background:Although intracranial Rosai–Dorfman disease is a principally benign lymphohistiocytosis, some patients run a relapsing or progressive course. However, reports about long-term follow-up are extremely rare.

“Microbleeding” from intracranial aneurysms: Local hemosiderin deposition identified during microsurgical treatment of unruptured intracranial aneurysms

Eric S. Nussbaum, Archie Defillo, Andrea Zelensky, Swaroopa Pulivarthi, Leslie Nussbaum

Date of publication: 27-Feb-2014

Background:During elective surgery for unruptured aneurysms, we have identified a group of patients with hemosiderin staining of the pial surface immediately adjacent to the aneurysm dome suggesting a remote and unrecognized history of microbleeding from the aneurysm. These cases form the basis for this report.

Pilomyxoid astrocytoma of the cerebellar vermis in an elderly patient

Branko Skovrlj, Margaret Pain, Joshua B. Bederson, Mary Fowkes

Date of publication: 27-Feb-2014

Background:Pilomyxoid astrocytoma (PMA) has recently been accepted as an aggressive variant of pilocytic astrocytoma with distinct histopathological features. PMAs have been frequently described in the pediatric population with a predilection for the hypothalamic/chiasmatic region.

Unusual hemodynamic stroke related to an accessory middle cerebral artery: The usefulness of fusion images from three-dimensional angiography

Kei Noguchi, Takachika Aoki, Satoru Komaki, Yasuharu Takeuchi, Masaru Hirohata, Motohiro Morioka

Date of publication: 26-Feb-2014

Background:Ischemic stroke associated with an anomaly of the middle cerebral artery (MCA) is a rare occurrence. The diagnosis is very difficult when there are steno-occlusive lesions associated with an accessory middle cerebral artery (AMCA).

A case of Langerhans cell histiocytosis of the skull in which preoperative methionine positron emission tomography was useful in comprehending the spreading of the lesion

Tetsu Yamaki, Yasuaki Kokubo, Yuki Saito, Kenichiro Matsuda, Hayato Funiu, Kaori Sakurada, Shinya Sato, Takamasa Kayama

Date of publication: 26-Feb-2014

Background:The problem with treatments against skull lesions of Langerhans cell histiocytosis (LCH) is that invasions often reach the bones and dura mater, making it difficult to accurately comprehend the range thereof prior to surgery. We herein report that 11C-methionine positron emission tomography (PET) (Met-PET) carried out prior to surgery was useful in comprehending the spreading of the lesion.

Subtotal resection of an intradural mature teratoma in an adult presenting with difficulty initiating micturition

Maria Kristina Vanguardia, Stephen Honeybul, Peter Robbins

Date of publication: 25-Feb-2014

Background:Teratomas are tumors comprised of tissues from all three germ layers. Teratomas within the spine are exceedingly rare especially in the absence of either spinal dysraphism, congenital abnormalities of the spine, spinal surgery, or history of lumbar punctures. Virchow was the first to describe this occurrence in the spine in 1863 and since then, only a handful of cases have been reported.

Conservative surgery for osteoid osteoma of the lumbar vertebrae

Tashfeen Ahmad, Muhammad Fawwad Ahmed Hussain, Ambreen A. Hameed, Nabeel Manzar, Riaz Hussain Lakdawala

Date of publication: 25-Feb-2014

Background:We present two patients with osteoid osteomas of the lumbar spine to highlight the delay in diagnosis and the utility of precise radiological localization enabling tumor resection without jeopardizing spinal stability.

Timing of cranioplasty after decompressive craniectomy for trauma

Mark P. Piedra, Andrew N. Nemecek, Brian T. Ragel

Date of publication: 25-Feb-2014

Background:The optimal timing of cranioplasty after decompressive craniectomy for trauma is unknown. The aim of this study was to determine if early cranioplasty after decompressive craniectomy for trauma reduces complications.