Neuroimaging markers of intracranial hypertension in cerebral venous thrombosis: A systematic review and meta-analysis

Abdulsalam M. Aleid, Abdulmonem A. Alhussain, Awn Abdulmohsen Alessa, Ibrahim Alahmed, Abdulmajeed Abdulaziz Aljabr, Hasan A. AlAidarous, Loai Albinsaad, Abdulrahman Almoslem, Saud Nayef Aldanyowi, Sami F. Almalki

Date of publication: 20-Jun-2025

Background: Cerebral venous thrombosis (CVT) is commonly associated with intracranial hypertension (IH), though its neuroimaging markers remain less well-defined. This study aims to systematically review and compare neuroimaging markers of IH in CVT and idiopathic IH (IIH) to better understand their diagnostic implications.

Assessing the predictability of isocitrate dehydrogenase mutational status in glioma patients using imaging features

Joao Meira Goncalves, André Miranda, Carolina Silva, Bruno Carvalho, Patricia Polónia, Paulo Linhares

Date of publication: 20-Jun-2025

Background: Radiogenomics, the intersection of imaging and genetics, is important in improving glioma diagnosis and treatment. This study aims to correlate imaging features with isocitrate dehydrogenase (IDH) mutation status, providing a non-invasive diagnostic tool to identify the genetic background of gliomas.

A case of recurrent spinal cord compression at craniocervical junction due to type IV mucopolysaccharidosis

Jun Hashimoto, Toshinari Kawasaki, Tamaki Kobayashi, Yoshihiko Ioroi, Motohiro Takayama

Date of publication: 20-Jun-2025

Background: Mucopolysaccharidosis type VI (MPS VI) is an autosomal recessive lysosomal genetic storage disorder caused by the accumulation of glycosaminoglycans in tissues and organs. A 10-month-old male with MPS VI had originally undergone foramen magnum decompression (FMD)/C1 followed by lifelong enzyme replacement therapy (ERT). At age 15, the patient underwent successful surgical treatment for retro-odontoid disease and recurrent cranio-cervical junction (CCJ) stenosis through a C1–C3 laminectomy and expansive duroplasty.

Parosteal lipoma of the supra-auricular region

Made Ratna Dewi, Christopher Lauren, I Nyoman Gde Wahyudana, Analysa Analysa, Ida Bagus Gede Adiguna Wibawa, I Gusti Ketut Agung Surya Kencana, Tjokorda Gde Bagus Mahadewa

Date of publication: 20-Jun-2025

Background: Parosteal lipomas are rare benign soft-tissue tumors that develop in close association with the periosteum. Skull involvement is exceptionally uncommon, with only a few cases reported in the literature.

Endoscopic-assisted surgical repair of ear cerebrospinal fluid leakage through a subtemporal craniotomy

Ramón López López, Emmanuel González Ruiz, Jesús Ricardo Cazadero Márquez

Date of publication: 20-Jun-2025

Background: CSF fistula involves abnormal leakage of cerebrospinal fluid (CSF) from its normal pathways, typically from high- to low-pressure areas at the base of the skull. It requires an osteomeningeal breach, causing discomforts such as headaches and abnormal drainage. Temporal bone CSF leakage often results from trauma or chronic otitis media, and its surgical treatment is often delayed. The application of endoscopes in skull base procedures has become increasingly common, offering new ways to improve visualization during performance. Endoscopic tools provide a broad view, sharp image quality, enhanced magnification, and the advantage of visualizing areas that are typically hard to see directly.

Spontaneous resolution of foramen magnum dural arteriovenous fistula with anticoagulant therapy: A case of antiphospholipid syndrome misdiagnosed as seronegative neuromyelitis optica spectrum disorder

Prasert Iampreechakul, Korrapakc Wangtanaphat, Songpol Chuntaroj, Chonlada Angsusing, Sirirat Khunvutthidee, Yodkhwan Wattanasen, Punjama Lertbutsayanukul, Sunisa Hangsapruek, Narupat Suanprasert, Surasak Komonchan, Somkiet Siriwimonmas

Date of publication: 20-Jun-2025

Background: Foramen magnum dural arteriovenous fistulas (FMDAVFs) are rare vascular lesions that often present with progressive myelopathy and can mimic inflammatory conditions such as neuromyelitis optica spectrum disorder (NMOSD). While endovascular or surgical treatment is typically required, spontaneous resolution of FMDAVFs is exceptionally rare. This case highlights the importance of considering vascular etiologies in patients with myelopathy and overlapping autoimmune features and explores the potential role of anticoagulant therapy in select cases.

Thoracic spinal epidural angiolipoma presenting with progressive paraparesis in an elderly patient

Haydar Gok, Kivanc Yangi, Omar Alomari, Uguray Payam Hacisalihoglu

Date of publication: 20-Jun-2025

Background: Spinal epidural angiolipomas (SEALs) are rare, benign tumors composed of mature adipocytes and abnormal vasculature, representing only 0.04–1.2% of spinal tumors. Predominantly located in the thoracic epidural space, they often cause progressive neurological deficits due to spinal cord compression, though acute deterioration may occur from hemorrhage or thrombosis. Misdiagnosis is common, and evidence-based management remains limited.

Visual symptoms after flow-diverter stenting of internal carotid artery aneurysms: A retrospective cohort study

Yuko Tanaka, Yoshikazu Matsuda, Tomoyuki Tsumoto, Tomoaki Terada

Date of publication: 20-Jun-2025

Background: Visual field defect and visual impairment are important but poorly characterized complications after flow-diverter (FD) stent placement for internal carotid artery (ICA) aneurysms.

Neuroplastic surgery for adulthood myelomeningocele: Advancement flap reconstruction

Erik Burgos-Sosa, Gustavo Melo-Guzman, Diana Carolina Paz-Hernandez, Miguel Jesus Bernes-Rodriguez, Ruben Acosta-Garces, Alfredo Lima-Romero, Mario Alberto Taylor-Martinez

Date of publication: 20-Jun-2025

Background: While it is widely recognized that surgical intervention is crucial at birth, the occurrence of giant myelomeningocele in adulthood is exceedingly uncommon. This case study aims to provide a comprehensive overview of a rare presentation of myelomeningocele accompanied by a tethered cord in an adult patient, highlighting the clinical features, diagnostic imaging, and surgical repair technique employed.

Glioma mimicking a cystic infectious disease: A case report of multifocal, multicentric cystic glioblastoma

Daniel Kiss-Bodolay, Marc Weiner, Kristof Egervari, Gilles Eperon, Maria Isabel Vargas, Denis Migliorini, Johannes Lobrinus, Stephan Harbarth, Philippe Bijlenga

Date of publication: 20-Jun-2025

Background: Glioblastoma multiforme (GBM) is a highly aggressive malignant tumor known to be a great mimicker. Multicystic metastasis and cystic GBM are not rare but multicystic diffuse GBM was never reported before.