- Department of Neurosurgery, San Filippo Neri Hospital, Roma, Italy
- Department of Neurosurgery, Carolina Neuroscience Institute, Raleigh, North Carolina, USA
Department of Neurosurgery, Carolina Neuroscience Institute, Raleigh, North Carolina, USA
DOI:10.4103/2152-7806.178521Copyright: © 2016 Surgical Neurology International This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
How to cite this article: Mastronardi L, Cacciotti G, Caputi F, Roperto R, Tonelli MP, Carpineta E, Fukushima T. Underlay hourglass-shaped autologous pericranium duraplasty in “key-hole” retrosigmoid approach surgery: Technical report. Surg Neurol Int 10-Mar-2016;7:25
How to cite this URL: Mastronardi L, Cacciotti G, Caputi F, Roperto R, Tonelli MP, Carpineta E, Fukushima T. Underlay hourglass-shaped autologous pericranium duraplasty in “key-hole” retrosigmoid approach surgery: Technical report. Surg Neurol Int 10-Mar-2016;7:25. Available from: http://surgicalneurologyint.com/surgicalint_articles/underlay-hourglass%e2%80%91shaped-autologous-pericranium-duraplasty-in-key%e2%80%91hole-retrosigmoid-approach-surgery-technical-report/
Background:Cerebrospinal fluid (CSF) leakages represent a major complication of skull base surgery. Watertight dural suture is challenging, and different ways to reinforce it have been proposed. Since 6 months, we use locally harvested autologous pericranium graft for dural repair in retrosigmoid approach.
Methods:Retrospectively, we analyzed 27 patients operated on with key-hole retrosigmoid approach from May 2014. In all, autologous pericranium was harvested and inserted as an underlay “hourglass-shaped” plug under the dura plane and stitched to dura. Surgical patch and sealant were used for augmentation. Complications considered were new neurological symptoms, surgical site infections, meningitis, CSF-leaks, and pseudomeningocele.
Results:Indications included tumor (16 cases), microvascular decompression (10 cases), and hemorrhagic cerebellar arteriovenous malformation (1 case). Surgical site infections, meningitis, and CSF leaks have never been observed. One neurofibromatosis type 2 patient operated on for large acoustic neuroma developed an asymptomatic pseudomeningocele, disappeared on 3-month magnetic resonance imaging follow-up.
Conclusions:In our series, autologous pericranium inserted and stitched as an underlay hourglass-shaped plug, augmented with surgical patch pieces and dural sealant seemed to be safe and effective for dural repair in “key-hole” retrosigmoid approach. With this technique, we obtained low complication rate, similar to the best current results of available literature.
Keywords: Autologous pericranium patch, cerebrospinal fluid-related complications, duraplasty, retrosigmoid approach
Postoperative cerebrospinal fluid (CSF) leakage is a challenging and potentially hazardous problem following many complex cranial procedures. This is, especially true for surgical approaches to posterior cranial fossa, in which a watertight dural reconstruction is not always feasible, and CSF pulsation waves are greater than other cranial areas.[
CSF fistulas into the soft tissues at the base of the skull can cause wound breakdown and/or pseudomeningocele, which often become very painful and debilitating. In addition, drainage of spinal fluid from the skin increases the risk for surgical site infections and meningitis.[
Autologous tissues for posterior cranial fossa dural closure have been mentioned in several articles.[
From May to October 2014, 27 consecutive patients were enrolled in the study. Indications for posterior fossa surgery have been cerebellopontine angle tumors in 16 cases (12 acoustic neuromas and 4 meningiomas), microvascular decompression for trigeminal neuralgia in 9 and for hemifacial spasm in 1, and bleeding left cerebellar arteriovenous malformation (AVM) associated with a left posterior inferior cerebellar artery aneurysm in 1 case. The age ranged from 20 to 77 years; 15 patients were female and 12 male.
“Key-hole” retrosigmoid approach
Except for the patient operated on for a hemorrhagic lateral cerebellar AVM, in which a supine position with 45° rotation of the head was used, in all patients a lateral Fukushima position was adopted.[
After a slightly curved 4–5 cm skin incision behind the ear, in all cases a free pericranial flap (about 3 cm × 3 cm) for dural closure was harvested [
Retromastoid lateral occipital bone was exposed including superior and inferior nuchal lines,[
At the end of the intracranial step and after meticulous hemostasis, the tack-up dural sutures applied during the dural opening phase were cut, and the autologous pericranium graft was inserted through the defect as an underlay hourglass-shaped plug. For obtaining this, the graft harvested had to be slightly larger than the dural defect, in order to have its edges under the dural plane. It was fixed under operative microscope magnification with separated stitches (with an “inside-to-outside” direction) to the dura mater, using a 3-0 running silk [
In all cases, the autologous bone removed or fitted titanium net was placed on the bony defect with dedicated miniscrews (Lorenz, Biomet Microfixation, Jacksonville, Florida, USA).
In this series, we never observed new neurological symptoms related to the described procedure of dural closure, surgical site infections, meningitis, and CSF leaks. The complication rate was 4%. One neurofibromatosis type 2-patient operated on for a right large acoustic neuroma developed an asymptomatic small pseudomeningocele on the 48-h-postoperative computed tomography scan; the CSF sac disappeared at the 3-month magnetic resonance imaging follow-up.
Techniques for posterior cranial fossa dural reconstruction and closure include many solutions. Synthetic dural patches applied with continuous or separate stitches, incorporation of autologous tissues (pericranium or fascia lata), augmentation with “muscle plugs” for small defects in the suture line and/or with gelatin sponge, absorbable hemostats, dural sealants. Temporary CSF diversion can be employed via a lumbar drain or external ventricular drain to reduce the pressure gradient across the dural closure until it “seals.”[
Even with these techniques, however, it is impossible to ensure a watertight dural closure for several reasons, including the holes in the dura created by surgical needle during suturing. “Onlay” applicable synthetic dural grafts should be avoided because of the high hydrodynamic pressure of CSF in this district.[
Chauvet et al.[
The nonaerosolized application of a thin layer of dural sealant (Duraseal®) to the dry dural surface, followed by a titanium mesh secured to the calvarium with microscrews, has been used by used Lam and Kasper[
The so-called surgical patch (TachoSil®, Takeda, Japan) combines the bioactive mechanism of action of fibrinogen and thrombin, with the mechanical support of a collagen patch. It is made from collagen, i.e. naturally reabsorbed, and is approved for hemostasis and for sealing of tissues. On contact with blood or other fluids, the coagulation factors react to form a fibrin clot that sticks the surgical patch to the tissue surface, producing an air- and liquid-tight seal in few minutes, providing protection against postoperative re-bleedings and leaks.[
Even if variety of dural substitutes is currently available, many data suggest that autologous materials are preferable compared to nonautologous substitutes.[
The technical tip we propose for dural closure after retrosigmoid approach is to insert a layer of autologous pericranium harvested during the opening step as an underlay hourglass-shaped plug, larger than the defect, under the dural plane, and to stitch it with an “inside-to-outside” direction to the dura mater [
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Conflicts of interest
There are no conflicts of interest.
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